ClamAV - One of the 'good' open source command line antivirus solution
This really makes my life easy if I want to deploy an upload server, or a mail server in UNIX and the files would be downloaded in WINDOWS or similar virus-prone operating systems. You can read more about it on the official website . A C-extension for python is available HERE to programmatically scan files and open pyclamd (daemon) socket. Θ Ω Sushant ♂